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2024, Vol: 14, Issue: 4
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Research Article 


Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan

Zakir Khan, Naveed Ahmed, Faiz Ullah Khan, Asim Ur-rehman, Hazir Rahman.


Cited By:2

Abstract
Objectives: To investigate the utilization pattern of Surgical antibiotic prophylaxis (SAP) for the prevention of surgical infections in most common abdominal and orthopedic surgical procedures.
Methods: A prospective observational and non-intervention study was conducted at two teaching hospitals (PIMS and SIH) in Islamabad, Pakistan. Prescriptions records were reviewed to assess the utilization pattern of SAP during the nine-month duration. Data regarding most common surgical procedures, antimicrobial utilization, dose, route and administration timing of SAP were extracted for analysis. Observed practices were compared with standard treatment guidelines.
Results: Out of total 1512 surgical procedures about, 56.9% (n=860) of patients performed abdominal followed by 652 (43.1%) orthopedic surgical procedures. A total of 212 (14%) surgical procedures were completely correct in all steps. SAP were given in 1474 (97.5%) of surgical procedures. In 712 of the participants (48.3%) were given Ceftriaxone following by Cefazolin (n=247, 16.7%). Abdominal surgeries were majorly managed with Ceftriaxone (59%) while the orthopedic surgeries managed with Ceftriaxone (31.3%) and Cefazolin (30%). Appropriate choice of SAP was observed in (n=275; 18.6%) procedures and about half (n=719, 49%) received antibiotics within optimal timing. The appropriate choice/selection of SAP according to the guidelines was greater in orthopedic surgical procedures (n=212; 14.8%) than abdominal surgeries (n=63; 4.3%); p≤0.001. Compliance with respect to timing was significantly lower in an orthopedic surgical procedure (n=301) as compared to abdominal surgeries (n=418); p≤0.001. Similarly, a statistically significant difference observed between PIMS and SIH with respect to SAP practices; p≤0.001.
Conclusions: Inappropriate choice, the timing of administration and combination of SAP were observed in the current study. J Microbiol Infect Dis 2019; 9(3):104-111.


 
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How to Cite this Article
Pubmed Style

Khan Z, Ahmed N, Khan FU, Ur-rehman A, Rahman H. Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. J Microbiol Infect Dis. 2019; 9(3): 104-111 . doi:10.5799/jmid.614180

Web Style

Khan Z, Ahmed N, Khan FU, Ur-rehman A, Rahman H. Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. https://www.jmidonline.org/?mno=302657195 [Access: January 09, 2025]. doi:10.5799/jmid.614180

AMA (American Medical Association) Style

Khan Z, Ahmed N, Khan FU, Ur-rehman A, Rahman H. Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. J Microbiol Infect Dis. 2019; 9(3): 104-111 . doi:10.5799/jmid.614180


Vancouver/ICMJE Style

Khan Z, Ahmed N, Khan FU, Ur-rehman A, Rahman H. Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. J Microbiol Infect Dis. (2019), [cited January 09, 2025]; 9(3): 104-111 . doi:10.5799/jmid.614180


Harvard Style

Khan, Z., Ahmed, . N., Khan, . F. U., Ur-rehman, . A. & Rahman, . H. (2019) Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. J Microbiol Infect Dis, 9 (3), 104-111 . doi:10.5799/jmid.614180


Turabian Style

Khan, Zakir, Naveed Ahmed, Faiz Ullah Khan, Asim Ur-rehman, and Hazir Rahman. 2019. Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. Journal of Microbiology and Infectious Diseases, 9 (3), 104-111 . doi:10.5799/jmid.614180


Chicago Style

Khan, Zakir, Naveed Ahmed, Faiz Ullah Khan, Asim Ur-rehman, and Hazir Rahman. "Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan." Journal of Microbiology and Infectious Diseases 9 (2019), 104-111 . doi:10.5799/jmid.614180


MLA (The Modern Language Association) Style

Khan, Zakir, Naveed Ahmed, Faiz Ullah Khan, Asim Ur-rehman, and Hazir Rahman. "Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan." Journal of Microbiology and Infectious Diseases 9.3 (2019), 104-111 . Print. doi:10.5799/jmid.614180


APA (American Psychological Association) Style

Khan, Z., Ahmed, . N., Khan, . F. U., Ur-rehman, . A. & Rahman, . H. (2019) Pattern of Surgical Antibiotic Prophylaxis for Surgical-site Infections in Most Common Surgical Procedures at Two Teaching Hospitals, Islamabad, Pakistan. Journal of Microbiology and Infectious Diseases, 9 (3), 104-111 . doi:10.5799/jmid.614180


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