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2024, Vol: 14, Issue: 4
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Case Report 


Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge

Sara Rebelo Casanova, Rita Paulino, Joana Tavares, Ana Cláudia Miranda, Raquel Sabino, Cristina Veríssimo, Cristina Toscano, Kamal Mansinho.


Abstract
Fungal infections are significant causes of morbidity and mortality in immunocompromised patients. Aspergillus spondylodiscitis is an uncommon manifestation of invasive aspergillosis and a significant cause of death and frailty.
We report a case of spondylodiscitis caused by Aspergillus nidulans section in an HIV patient with Burkitt 's lymphoma, who presented with long-term lower back pain and weakness of the lower limbs. Initial MR imaging missed the lesion. Emergent decompression surgery was performed. Fungal culture on the vertebral disc revealed the agent that was later confirmed by sequencing the ITS region of ribosomal DNA genes. Voriconazole was the chosen treatment, and the patient improved. This case demonstrates how difficult a diagnosis can be if we are not considering it. J Microbiol Infect Dis 2021; 11(3):162-165.

Key words: Aspergillus nidulans section, Spondylodiscitis, Voriconazole


 
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How to Cite this Article
Pubmed Style

Casanova SR, Paulino R, Tavares J, Miranda AC, Sabino R, Veríssimo C, Toscano C, Mansinho K. Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. J Microbiol Infect Dis. 2021; 11(3): 162-165 . doi:10.5799/jmid.993989

Web Style

Casanova SR, Paulino R, Tavares J, Miranda AC, Sabino R, Veríssimo C, Toscano C, Mansinho K. Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. https://www.jmidonline.org/?mno=302657341 [Access: January 09, 2025]. doi:10.5799/jmid.993989

AMA (American Medical Association) Style

Casanova SR, Paulino R, Tavares J, Miranda AC, Sabino R, Veríssimo C, Toscano C, Mansinho K. Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. J Microbiol Infect Dis. 2021; 11(3): 162-165 . doi:10.5799/jmid.993989


Vancouver/ICMJE Style

Casanova SR, Paulino R, Tavares J, Miranda AC, Sabino R, Veríssimo C, Toscano C, Mansinho K. Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. J Microbiol Infect Dis. (2021), [cited January 09, 2025]; 11(3): 162-165 . doi:10.5799/jmid.993989


Harvard Style

Casanova, S. R., Paulino, . R., Tavares, . J., Miranda, . A. C., Sabino, . R., Veríssimo, . C., Toscano, . C. & Mansinho, . K. (2021) Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. J Microbiol Infect Dis, 11 (3), 162-165 . doi:10.5799/jmid.993989


Turabian Style

Casanova, Sara Rebelo, Rita Paulino, Joana Tavares, Ana Cláudia Miranda, Raquel Sabino, Cristina Veríssimo, Cristina Toscano, and Kamal Mansinho. 2021. Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. Journal of Microbiology and Infectious Diseases, 11 (3), 162-165 . doi:10.5799/jmid.993989


Chicago Style

Casanova, Sara Rebelo, Rita Paulino, Joana Tavares, Ana Cláudia Miranda, Raquel Sabino, Cristina Veríssimo, Cristina Toscano, and Kamal Mansinho. "Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge." Journal of Microbiology and Infectious Diseases 11 (2021), 162-165 . doi:10.5799/jmid.993989


MLA (The Modern Language Association) Style

Casanova, Sara Rebelo, Rita Paulino, Joana Tavares, Ana Cláudia Miranda, Raquel Sabino, Cristina Veríssimo, Cristina Toscano, and Kamal Mansinho. "Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge." Journal of Microbiology and Infectious Diseases 11.3 (2021), 162-165 . Print. doi:10.5799/jmid.993989


APA (American Psychological Association) Style

Casanova, S. R., Paulino, . R., Tavares, . J., Miranda, . A. C., Sabino, . R., Veríssimo, . C., Toscano, . C. & Mansinho, . K. (2021) Spondylodiscitis by Aspergillus nidulans: A Diagnostic Challenge. Journal of Microbiology and Infectious Diseases, 11 (3), 162-165 . doi:10.5799/jmid.993989


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