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2024, Vol: 14, Issue: 4
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Case Report 


The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc.


Cited By:2

Abstract
The pegylated interferon alpha and ribavirin treatment is well established therapy for hepatitis C virus (HCV) infection. During the treatment alanine aminotransferase (ALT) lare may be observed rarely. A 51-year-old female receiving pegylated interferon and ribavirin therapy for HCV infection, complained nausea, vomiting in seventh week of the therapy, and her ALT level was detected over 20 times above the normal level. Hepatitis B surface antigen, anti-nuclear antibody, anti-mitochondrial antibody, anti-double stranded DNA antibody and anti-hepatitis A virus IgM antibody were negative, and thyroid stimulating hormone was normal. HCV RNA level was 424 IU/ml. PEG IFN and ribavirin therapy was interrupted for three weeks, after liver enzyme level was detected less than 100U/L, the treatment was resumed. The patient was followed up for 2 months, ALT lare was not observed. In conclusion, we present a rare case with ALT lare, while receiving pegylated interferon and ribavirin therapy for chronic HCV infection. J Microbiol Infect Dis 2012; 2(3): 121-123


 
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How to Cite this Article
Pubmed Style

Demiraslan H, Ture Z, Kılıc AU. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis. 2012; 2(3): 121-123 . doi:10.5799/jmid2012.03.0056

Web Style

Demiraslan H, Ture Z, Kılıc AU. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. https://www.jmidonline.org/?mno=302657283 [Access: January 09, 2025]. doi:10.5799/jmid2012.03.0056

AMA (American Medical Association) Style

Demiraslan H, Ture Z, Kılıc AU. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis. 2012; 2(3): 121-123 . doi:10.5799/jmid2012.03.0056


Vancouver/ICMJE Style

Demiraslan H, Ture Z, Kılıc AU. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis. (2012), [cited January 09, 2025]; 2(3): 121-123 . doi:10.5799/jmid2012.03.0056


Harvard Style

Demiraslan, H., Ture, . Z. & Kılıc, . A. U. (2012) The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis, 2 (3), 121-123 . doi:10.5799/jmid2012.03.0056


Turabian Style

Demiraslan, Hayati, Zeynep Ture, and Aysegul Ulu Kılıc. 2012. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. Journal of Microbiology and Infectious Diseases, 2 (3), 121-123 . doi:10.5799/jmid2012.03.0056


Chicago Style

Demiraslan, Hayati, Zeynep Ture, and Aysegul Ulu Kılıc. "The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin." Journal of Microbiology and Infectious Diseases 2 (2012), 121-123 . doi:10.5799/jmid2012.03.0056


MLA (The Modern Language Association) Style

Demiraslan, Hayati, Zeynep Ture, and Aysegul Ulu Kılıc. "The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin." Journal of Microbiology and Infectious Diseases 2.3 (2012), 121-123 . Print. doi:10.5799/jmid2012.03.0056


APA (American Psychological Association) Style

Demiraslan, H., Ture, . Z. & Kılıc, . A. U. (2012) The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. Journal of Microbiology and Infectious Diseases, 2 (3), 121-123 . doi:10.5799/jmid2012.03.0056


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Journal of Microbiology and Infectious Diseases

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Faculty of Veterinary Medicine

University of Tripoli

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