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2024, Vol: 14, Issue: 4
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Research Article 


Group B streptococcus detection in China: comparison of different screening methods and different sampling sites

Xi Wang, Yingna Song, Liangkun Ma, Juntao Liu, Yingchun Xu, Jie Yi.


Abstract
Objectives: To evaluate the use of real-time polymerase chain reaction (RT-PCR) and bacterial culture methods to detect group B streptococcus (GBS) in Chinese pregnant women in the third trimester; to separately assess the prevalence of rectal and vaginal GBS colonization ; and to determine the antimicrobial susceptibility pattern of the isolates.
Methodology: Samples were collected from 505 women at 35 and 37 weeks gestation at the Peking Union Medical College Hospital. Bacterial culture and RT-PCR were performed. Antimicrobial susceptibility to commonly used antibiotics was also analyzed.
Results: The overall GBS colonization rate was 7.5%. The colonization rate, sensitivity, and negative predictive value of the bacterial culture method were 2.8%, 36.8%, and 95.1%, respectively, and these values were 7.3%, 97.4%, and 99.8%, respectively, for PCR (p<0.001). The GBS colonization rate of the rectum (6.7%) was higher than that of the vagina (2.8%) (p=0.005). Antimicrobial susceptibility testing showed that 100% were sensitive to penicillin, cephalosporin and vancomycin.
Conclusions: RT-PCR was found to be a rapid and sensitive test for the detection of GBS colonization in Chinese pregnant women. Rectal swabbing was also important for detecting GBS colonization. β-lactams are the first-line antibiotics used for the treatment of GBS. J Microbiol Infect Dis 2016;6(4): 179-183

Key words: Group B streptococcus; Real-time polymerase chain reaction; Sampling sites


 
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How to Cite this Article
Pubmed Style

Wang X, Song Y, Ma L, Liu J, Xu Y, Yi J. Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. J Microbiol Infect Dis. 2016; 6(4): 179-183 . doi:10.5799/jmid.vi.328930

Web Style

Wang X, Song Y, Ma L, Liu J, Xu Y, Yi J. Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. https://www.jmidonline.org/?mno=302657189 [Access: January 09, 2025]. doi:10.5799/jmid.vi.328930

AMA (American Medical Association) Style

Wang X, Song Y, Ma L, Liu J, Xu Y, Yi J. Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. J Microbiol Infect Dis. 2016; 6(4): 179-183 . doi:10.5799/jmid.vi.328930


Vancouver/ICMJE Style

Wang X, Song Y, Ma L, Liu J, Xu Y, Yi J. Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. J Microbiol Infect Dis. (2016), [cited January 09, 2025]; 6(4): 179-183 . doi:10.5799/jmid.vi.328930


Harvard Style

Wang, X., Song, . Y., Ma, . L., Liu, . J., Xu, . Y. & Yi, . J. (2016) Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. J Microbiol Infect Dis, 6 (4), 179-183 . doi:10.5799/jmid.vi.328930


Turabian Style

Wang, Xi, Yingna Song, Liangkun Ma, Juntao Liu, Yingchun Xu, and Jie Yi. 2016. Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. Journal of Microbiology and Infectious Diseases, 6 (4), 179-183 . doi:10.5799/jmid.vi.328930


Chicago Style

Wang, Xi, Yingna Song, Liangkun Ma, Juntao Liu, Yingchun Xu, and Jie Yi. "Group B streptococcus detection in China: comparison of different screening methods and different sampling sites." Journal of Microbiology and Infectious Diseases 6 (2016), 179-183 . doi:10.5799/jmid.vi.328930


MLA (The Modern Language Association) Style

Wang, Xi, Yingna Song, Liangkun Ma, Juntao Liu, Yingchun Xu, and Jie Yi. "Group B streptococcus detection in China: comparison of different screening methods and different sampling sites." Journal of Microbiology and Infectious Diseases 6.4 (2016), 179-183 . Print. doi:10.5799/jmid.vi.328930


APA (American Psychological Association) Style

Wang, X., Song, . Y., Ma, . L., Liu, . J., Xu, . Y. & Yi, . J. (2016) Group B streptococcus detection in China: comparison of different screening methods and different sampling sites. Journal of Microbiology and Infectious Diseases, 6 (4), 179-183 . doi:10.5799/jmid.vi.328930


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