E-ISSN 2146-9369 | ISSN 2146-3158
 

Case Report 


The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc.

Cited By:2

Abstract
The pegylated interferon alpha and ribavirin treatment is well established therapy for hepatitis C virus (HCV) infection. During the treatment alanine aminotransferase (ALT) lare may be observed rarely. A 51-year-old female receiving pegylated interferon and ribavirin therapy for HCV infection, complained nausea, vomiting in seventh week of the therapy, and her ALT level was detected over 20 times above the normal level. Hepatitis B surface antigen, anti-nuclear antibody, anti-mitochondrial antibody, anti-double stranded DNA antibody and anti-hepatitis A virus IgM antibody were negative, and thyroid stimulating hormone was normal. HCV RNA level was 424 IU/ml. PEG IFN and ribavirin therapy was interrupted for three weeks, after liver enzyme level was detected less than 100U/L, the treatment was resumed. The patient was followed up for 2 months, ALT lare was not observed. In conclusion, we present a rare case with ALT lare, while receiving pegylated interferon and ribavirin therapy for chronic HCV infection. J Microbiol Infect Dis 2012; 2(3): 121-123


 
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How to Cite this Article
Pubmed Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis. 2012; 2(3): 121-123 . doi:10.5799/jmid2012.03.0056


Web Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. https://www.jmidonline.org/?mno=302657283 [Access: February 03, 2024]. doi:10.5799/jmid2012.03.0056


AMA (American Medical Association) Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis. 2012; 2(3): 121-123 . doi:10.5799/jmid2012.03.0056



Vancouver/ICMJE Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis. (2012), [cited February 03, 2024]; 2(3): 121-123 . doi:10.5799/jmid2012.03.0056



Harvard Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc (2012) The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. J Microbiol Infect Dis, 2 (3), 121-123 . doi:10.5799/jmid2012.03.0056



Turabian Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. 2012. The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. Journal of Microbiology and Infectious Diseases, 2 (3), 121-123 . doi:10.5799/jmid2012.03.0056



Chicago Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. "The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin." Journal of Microbiology and Infectious Diseases 2 (2012), 121-123 . doi:10.5799/jmid2012.03.0056



MLA (The Modern Language Association) Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc. "The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin." Journal of Microbiology and Infectious Diseases 2.3 (2012), 121-123 . Print. doi:10.5799/jmid2012.03.0056



APA (American Psychological Association) Style

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc (2012) The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin. Journal of Microbiology and Infectious Diseases, 2 (3), 121-123 . doi:10.5799/jmid2012.03.0056