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2024, Vol: 14, Issue: 1
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Case Report 


Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary.

Cited By:2

Abstract
We report a case of a 40-year-old male patient who developed a fever one week after recovering from severe COVID-19 illness that had needed treatment with injectable corticosteroids and Tocilizumab. The patient had had maculopapular lesions on his trunk months before contracting COVID-19, but the skin lesions progressed along with the post-covid fever. Detailed workup and biopsy from skin lesions on the face, trunk, and bone marrow revealed Histoplasmosis. This case highlights the possibility of flaring up of Histoplasmosis in COVID-19 patients who have been treated with immunosuppressants. In our case, the plausible reason for reactivation and growth of Histoplasma may be the suppression of IL6 action by Tocilizumab.<br>It may be prudent to screen patients for Histoplasma and other fungal infections like aspergillus before administering an immune-suppressive regimen in patients with a moderate or severe COVID-19 illness. Urinary Histoplasma antigen may be used for screening in these patients. J Microbiol Infect Dis 2021; 11(3):170-173.

Key words: COVID-19, IL6 inhibitor, Histoplasmosis


 
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How to Cite this Article
Pubmed Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. J Microbiol Infect Dis. 2021; 11(3): 170-173 . doi:10.5799/jmid.994001

Web Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. https://www.jmidonline.org/?mno=302657247 [Access: February 03, 2024]. doi:10.5799/jmid.994001

AMA (American Medical Association) Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. J Microbiol Infect Dis. 2021; 11(3): 170-173 . doi:10.5799/jmid.994001


Vancouver/ICMJE Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. J Microbiol Infect Dis. (2021), [cited February 03, 2024]; 11(3): 170-173 . doi:10.5799/jmid.994001


Harvard Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary (2021) Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. J Microbiol Infect Dis, 11 (3), 170-173 . doi:10.5799/jmid.994001


Turabian Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. 2021. Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. Journal of Microbiology and Infectious Diseases, 11 (3), 170-173 . doi:10.5799/jmid.994001


Chicago Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. "Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient." Journal of Microbiology and Infectious Diseases 11 (2021), 170-173 . doi:10.5799/jmid.994001


MLA (The Modern Language Association) Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary. "Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient." Journal of Microbiology and Infectious Diseases 11.3 (2021), 170-173 . Print. doi:10.5799/jmid.994001


APA (American Psychological Association) Style

Brijesh Sharma, Premapassan Krishnamurthy, Desh Deepak, Shailja Shukla, Vishakha Arya, Anuradha Chowdhary (2021) Disseminated Histoplasmosis Post-IL6 Inhibitor Use in A COVID-19 Patient. Journal of Microbiology and Infectious Diseases, 11 (3), 170-173 . doi:10.5799/jmid.994001


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Journal of Microbiology and Infectious Diseases

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