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Case Report 


First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani.

Abstract
Salmonella enterica serovar Typhi (S. Typhi) is one of the typhoidal Salmonellae that causes typhoid fever. We report the first case of an XDR S. Typhi in a suspected case of Endocarditis with Aortic Valve Replacement and deranged INR. The identification was carried out by an automated system. The antibiogram was performed according to CLSI recommendations. The XDR S. Typhi isolates were found resistant to Azithromycin. Although XDR S. Typhi has been reported in our country and elsewhere, however, till to date no complete resistant isolate of S. Typhi to Azithromycin has been reported in Pakistan. The patient had a smooth recovery on intravenous meropenem. The case highlights the importance of the acquisition of resistance to the last line antibiotics in S. Typhi in our country and is of concern to infectious disease specialists to ensure infection control to avoid its spread. J Microbiol Infect Dis 2021; 11(1):32-35.

Key words: Salmonella, XDR S. Typhi, Azithromycin


 
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How to Cite this Article
Pubmed Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. J Microbiol Infect Dis. 2021; 11(1): 32-35 . doi:10.5799/jmid.897210


Web Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. https://www.jmidonline.org/?mno=302657233 [Access: February 02, 2024]. doi:10.5799/jmid.897210


AMA (American Medical Association) Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. J Microbiol Infect Dis. 2021; 11(1): 32-35 . doi:10.5799/jmid.897210



Vancouver/ICMJE Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. J Microbiol Infect Dis. (2021), [cited February 02, 2024]; 11(1): 32-35 . doi:10.5799/jmid.897210



Harvard Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani (2021) First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. J Microbiol Infect Dis, 11 (1), 32-35 . doi:10.5799/jmid.897210



Turabian Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. 2021. First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. Journal of Microbiology and Infectious Diseases, 11 (1), 32-35 . doi:10.5799/jmid.897210



Chicago Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. "First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement." Journal of Microbiology and Infectious Diseases 11 (2021), 32-35 . doi:10.5799/jmid.897210



MLA (The Modern Language Association) Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani. "First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement." Journal of Microbiology and Infectious Diseases 11.1 (2021), 32-35 . Print. doi:10.5799/jmid.897210



APA (American Psychological Association) Style

Arif Maqsood Ali, Agha Babar Hussain, Azhar Mehmood Kayani (2021) First Case of Azithromycin Resistance in Salmonella Typhi, Isolated in a Patient with Prosthetic Valve Replacement. Journal of Microbiology and Infectious Diseases, 11 (1), 32-35 . doi:10.5799/jmid.897210