E-ISSN 2146-9369 | ISSN 2146-3158
 
2024, Vol: 14, Issue: 1
14 / 1Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles

Research Article 


Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo.

Abstract
Objectives: Acute diarrhea is among the leading causes of mortality and morbidity worldwide. Bacteria tend to cause more fatal illnesses and complications such as septicemia and persistent diarrhea. This study aimed to determine the causes of acute diarrhea, laboratory and clinical predictors of bacterial causes, and antimicrobial resistance pattern among the isolates among children in Dar es salaam, Tanzania.<br>Methods: A cross-sectional hospital-based study was conducted in Dar es salaam Hospitals from April 2015 to March 2016 among children below five years of age who presented with acute diarrhea. Demographic characteristics and results from stool specimen analysis, complete blood count, C- reactive protein and antimicrobial resistance results were recorded using a pre-structured clinical research form.<br>Results: Among 200 children enrolled, viruses were identified in 149 (74.5%) of the cases. Bacterial pathogens were found in 15 (7.5%) cases only. Elevated stool red blood cell count, stool white blood cell count, and fever were highly associated with enteric bacterial pathogens (p<0.001, p=0.002 and p=0.04 respectively). Most of the bacterial isolates were resistant to Cotrimoxazole and erythromycin but highly sensitive to ciprofloxacin and Ceftriaxone.<br>Conclusion: Fever, elevated stool leukocyte and elevated stool red blood cells are significant predictors of bacterial enteric pathogens in children with acute diarrhea. These parameters may guide clinicians in resource-limited settings in the diagnosis and management of acute diarrhea. Further studies should be conducted to determine local antimicrobial resistance patterns. J Microbiol Infect Dis 2020; 10(3):208-214.

Key words: Acute diarrhea, causes, predictors, antimicrobial resistance, children


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Florence Salvatory Kalabamu
Articles by Paulinne Lukumo Mpongo
Articles by Esther Daniel Mwaikambo
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. J Microbiol Infect Dis. 2020; 10(4): 208-214 . doi:10.5799/jmid.839445

Web Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. https://www.jmidonline.org/?mno=302657037 [Access: February 03, 2024]. doi:10.5799/jmid.839445

AMA (American Medical Association) Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. J Microbiol Infect Dis. 2020; 10(4): 208-214 . doi:10.5799/jmid.839445


Vancouver/ICMJE Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. J Microbiol Infect Dis. (2020), [cited February 03, 2024]; 10(4): 208-214 . doi:10.5799/jmid.839445


Harvard Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo (2020) Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. J Microbiol Infect Dis, 10 (4), 208-214 . doi:10.5799/jmid.839445


Turabian Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. 2020. Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. Journal of Microbiology and Infectious Diseases, 10 (4), 208-214 . doi:10.5799/jmid.839445


Chicago Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. "Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.." Journal of Microbiology and Infectious Diseases 10 (2020), 208-214 . doi:10.5799/jmid.839445


MLA (The Modern Language Association) Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo. "Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.." Journal of Microbiology and Infectious Diseases 10.4 (2020), 208-214 . Print. doi:10.5799/jmid.839445


APA (American Psychological Association) Style

Florence Salvatory Kalabamu, Paulinne Lukumo Mpongo, Esther Daniel Mwaikambo (2020) Acute Diarrhea in Children Less than Five Years of Age in Dar es Salaam: Causes, Clinical, and Laboratory Predictors of Bacterial Pathogens.. Journal of Microbiology and Infectious Diseases, 10 (4), 208-214 . doi:10.5799/jmid.839445


Author LoginReviewer LoginAbout PublisherOpen Access PolicyEditorial PoliciesPeer Review PolicyPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About Journal of Microbiology and Infectious Diseases

Journal of Microbiology and Infectious Diseases (JMID) is an international "peer review" journal in microbiology, infectious diseases, virology, ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes

Editor-in-Chief

Journal of Microbiology and Infectious Diseases

Department of Microbiology and Parasitology 

Faculty of Veterinary Medicine

University of Tripoli

P.O. Box 13662, Tripoli, Libya