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2024, Vol: 14, Issue: 2
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Research Article


Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria

Lawrence Shola Owolabi, Cajethan Onyebuchi Ezeamagu, Godswill Nduka Anyasor.


Abstract
Background:
Antibiotic resistance is a global problem with high morbidity and mortality in healthcare institution that requires an antimicrobial alternative and ittle is known of antibacterial agents derived from insect sources.
Aim:
The aim of the study was to examined antibacterial properties of secondary metabolites from insect-associated bacteria.
Methods:
Thirty-three wasps were obtained from abandoned structures in a local Community. Bacteria were isolated and identified by Sanger sequencing method. The metabolites were extracted and antibacterial potential was tested against different pathogens. The metabolites concentration was analyzed via High Performance Liquid Chromatography (HPLC). The metabolites and their clinical potentials were explored through STRING analysis.
Results:
Fifteen bacteria were isolated and 9 exhibited antibacterial properties consisting of Enterococcus faecalis (2). Pseudomonas fragi (2), Propionibacterium spp (1), Comamonas terrigena (2), Staphylococcus galinarum (1), Levi lactobacillus brevis (1). Antibiogram revealed that the secondary metabolite had inhibitory effects against all pathogens. The HPLC results indicated that the control and metabolites were eluted at 1.288 and 1.259 mins respectively with concentration ranging from 16.68 to 4761.82 mg/l. STRING analysis showed that the metabolites were gallidermin, enterocin, propionicin, and phenazine.
Conclusion:
The study concluded that the metabolites show activity against test strains and therefore a source of novel antimicrobials for addressing the global drug-resistant pathogens.

Key words: Antibacterial Properties, Gallidermin, Secondary metabolites, Wasp-associated bacteria


 
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How to Cite this Article
Pubmed Style

Owolabi LS, Ezeamagu CO, Anyasor GN. Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. J Microbiol Infect Dis. 2024; 14(2): 80-87. doi:10.5455/JMID.2024.v14.i2.6

Web Style

Owolabi LS, Ezeamagu CO, Anyasor GN. Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. https://www.jmidonline.org/?mno=196205 [Access: July 05, 2024]. doi:10.5455/JMID.2024.v14.i2.6

AMA (American Medical Association) Style

Owolabi LS, Ezeamagu CO, Anyasor GN. Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. J Microbiol Infect Dis. 2024; 14(2): 80-87. doi:10.5455/JMID.2024.v14.i2.6


Vancouver/ICMJE Style

Owolabi LS, Ezeamagu CO, Anyasor GN. Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. J Microbiol Infect Dis. (2024), [cited July 05, 2024]; 14(2): 80-87. doi:10.5455/JMID.2024.v14.i2.6


Harvard Style

Owolabi, L. S., Ezeamagu, . C. O. & Anyasor, . G. N. (2024) Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. J Microbiol Infect Dis, 14 (2), 80-87. doi:10.5455/JMID.2024.v14.i2.6


Turabian Style

Owolabi, Lawrence Shola, Cajethan Onyebuchi Ezeamagu, and Godswill Nduka Anyasor. 2024. Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. Journal of Microbiology and Infectious Diseases, 14 (2), 80-87. doi:10.5455/JMID.2024.v14.i2.6


Chicago Style

Owolabi, Lawrence Shola, Cajethan Onyebuchi Ezeamagu, and Godswill Nduka Anyasor. "Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria." Journal of Microbiology and Infectious Diseases 14 (2024), 80-87. doi:10.5455/JMID.2024.v14.i2.6


MLA (The Modern Language Association) Style

Owolabi, Lawrence Shola, Cajethan Onyebuchi Ezeamagu, and Godswill Nduka Anyasor. "Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria." Journal of Microbiology and Infectious Diseases 14.2 (2024), 80-87. Print. doi:10.5455/JMID.2024.v14.i2.6


APA (American Psychological Association) Style

Owolabi, L. S., Ezeamagu, . C. O. & Anyasor, . G. N. (2024) Antibacterial properties of secondary metabolites produced from wasp-associated bacteria in Isara, Remo-North, Ogun State, Nigeria. Journal of Microbiology and Infectious Diseases, 14 (2), 80-87. doi:10.5455/JMID.2024.v14.i2.6


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