eISSN : 2146-9369
Creative Commons Lisansı
Journal of Clinical and Experimental Investigations is licenced under the terms of Creative Commons Attribution-Non Commercial4.0 International (CC BY-NC 4.0) License.
Abstract - Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate
Dr Jayashree Purkayastha, Dr Leslie Edward Lewis, Dr Ramesh Bhat Y, Dr Morakhia Jwalit V, Dr Ranjan Shetty K, Dr Muhammad Najih L

Jayashree Purkayastha,

Department of Paediatrics, Kasturba Medical College, Manipal University, Manipal, 576 104 Karnataka, India     

Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate

ABSTRACT

Fungal mycetoma or endocarditis is rare in premature neonates and it is often associated with high mortality. In the majority of the cases diagnosis is made postmortem. Here we report a 30-week-old preterm neonate who developed Candida albicans blood stream infection complicated by endocarditis and subsequent mycetoma. Initially, this neonate had Klebsiella sepsis requiring multiple antibiotic courses. A peripherally inserted central venous catheter was used to give total parenteral nutrition. On day 24 of life, he developed candidemia, treated with 14 day course of fluconazole and shown improvement. Further, on day 60 of life he developed cholestasis, deranged liver function tests and persis­tent thrombocytopenia along with apnea, bradycardia and desaturations. Blood culture again grew again C. albicans. Echocardiography showed large fungal vegetation on tricuspid valve with a mycetoma filling the right ventricle. He was treated with intravenous amphotericin B, fluconazole and supportive measures, but he deteriorated and succumbed after 2 weeks. J Microbiol Infect Dis 2015;5(3): 142-145

Jayashree Purkayastha, Department of Paediatrics, Kasturba Medical College, Manipal University, Manipal, 576 104 Karnataka, India, Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate, Jayashree Purkayastha, Department of Paediatrics, Kasturba Medical College, Manipal University, Manipal, 576 104 Karnataka, India  J Microbiol Infect Dis 2015;5(3): 142-145 doi: 10.5799/ahinjs.02.2015.03.0194

Volume 05, Number 03 (2015)

Volume 05, Number 03 (2015)