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Journal of Clinical and Experimental Investigations is licenced under the terms of Creative Commons Attribution-Non Commercial4.0 International (CC BY-NC 4.0) License.
Abstract - A rare cause of fever and icterus: Thyroid crisis
Emine Parlak, Serpil Erol

Thyroid crisis is the severe form of hyperthyroidism. The predisposing factors are mostly surgeries and additional diseases. Although the case is rare, the mortality rate is high. Here, we present a thyroid crisis case which implies infectious diseases. A 36-year-old female patient admitted to the hospital with high fever, abdominal pain, and unstable mental state. Physical examination revealed icterus, tachycardia, and hepatosplenomegaly. Serum free triiodothyronine (FT3), and free thyroxine (FT4) levels were elevated and thyroid-stimulating hormone (TSH) was highly suppressed. An infectious etiology was suspected on admission, but further investigation revealed thyroid crisis. Patients with high fever should be considered in differential diagnosis of non-infectious causes such as thyroid crisis. In these cases, early and correct diagnosis is important for prognosis. 

Volume 03, Number 01 (2013)