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Abstract - Diagnosis of extra-pulmonary Tuberculosis by MTB/RIF from a fine needle aspirate biopsy: a case report
Abubakar Tukur Dawakin Kudu, Sani Iliya, Akinfenwa Atanda Taofeq, Nasiru Abdullahi Ismail, Abdurrahaman Abba Sheshe

Diagnosis of Extra-Pulmonary Tuberculosis by MTB/RIF from a Fine Needle Aspirate Biopsy: Case Report

Abubakar Tukur Dawakin Kudu1, Sani Iliya2, Akinfenwa Taofeq Atanda3, Nasiru Abdullahi Ismail4, Abdurrahman Abba Shehe4

1North West Zonal Tuberculosis Reference Laboratory, Aminu Kano Teaching Hospital, Kano, Kano, Nigeria

2Department of Biological Sciences, School of Pure and Applied Sciences, Mount Kenya University, Thika, Kenya

3Department of Pathology, Aminu Kano Teaching Hospital, Kano, Kano, Nigeria

4Department of Surgery, Aminu Kano Teaching Hospital, Kano, Kano, Nigeria

4Department of Surgery, Aminu Kano Teaching Hospital, Kano, Kano, Nigeria



Tuberculosis lymphadenitis is the frequent form of extra pulmonary tuberculosis (EPTB). Fine needle technique is easy to be carried out by trained healthcare workers in resources limited setting like Nigeria. This case report was aimed to highlight use and challenges of fine-needle aspirate biopsy (FNAB) for GeneXpert MTB/RIF assay in the diagnosis of EPTB. Fine needle aspirate was taken from left lymph node and processed for cytological staining with Diff Quik and Ziehl Neelsen stains (ZN) as well as GeneXpert molecular assay. The Diff Quick and ZN showed necrotic debris with epithelioid histiocytes and occasional giant cells while ZN was negative. GeneXpert result reveals Mycobacterium tuberculosis Complex and Rifampicin resistance not detected. These findings provided quick and effective means of diagnosis of EPTB especially from FNAB which has not been commonly undertaken in resource limited Nigeria. J Microbiol Infect Dis 2020; 10(1):59-61.

Keywords: Tuberculous lymphadenitis, Mycobacterium tuberculosis, Xpert MTB/RIF assay, Fine-needle aspirate biopsy

Volume 10, Number 01 (2020)