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Abstract - Streptococcus constellatus causing mycotic aneurysm in a patient with diffuse large B cell lymphoma
Nadeem Raja, Sunil Gupta, Albena Nikolava, Simon Weston-Smith, theo Raudsepp, Hizbullah Sheikh

Streptococcus constellatus Causing Mycotic Aneurysm in A Patient with Diffuse Large B-Cell Lymphoma

Nadeem Sajjad Raja1, Albena Nikolova2, Theo Raudsepp3, Simon G Weston-Smith2, Annette Rumbold2, Hizbullah Shaikh4, Sunil Gupta2

1Department of Microbiology, East Sussex Healthcare Trust, Hastings, United Kingdom

2Department of Clinical Haematology, East Sussex Healthcare Trust, Hastings, United Kingdom

3Department of Radiology, East Sussex Healthcare Trust, Hastings, United Kingdom

4Department of Histopathology , Kings College Hospital, London, United Kingdom


This is a first case of mycotic aneurysm due to Streptococcus constellatus in a 58 years old male patient with diffuse large B cell lymphoma. A mycotic aneurysm is a rare but life threatening and potentially fatal sequela of bacteraemia. A 58-year male patient initially presented with sepsis after 7 days of chemotherapy. No clear focus of sepsis was found. Blood culture grew Streptococcus constellatus. He received appropriate antibiotic and discharged well. He represented after 5 days with excruciating intrascapular and chest pain. This patient with haematology malignancy had radiologically, surgically and histologically confirmed mycotic aneurysm that involved ascending aorta which contained pseudoaneurysm. Patient was treated excision of the infected tissue and aortic graft, and long term antibiotics. This rare case highlights that the high clinical suspicion in patients presenting with possibly mycotic aneurysm is a critical tool in addition to perfect surgical treatment and medical treatment with adequate antibiotics. J Microbiol Infect Dis 2017; 7(4):213-216

Keywords: Mycotic aneurysm, blood stream infections, cancer, diffuse large B cell lymphoma

Volume 07, Number 04 (2017)