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Abstract - Hemophagocytic Syndrome Associated with Herpes Virus 8 and Multicentric Castleman Disease in A HIV Negative Patient
Arturo Gonzalez Raya, Eva Martin Salido, Miguel F Cantero Sánchez, Gonzalo Callejón Martín, María L Hortas Nieto

Hemophagocytic Syndrome Associated with Herpes Virus 8 and Multicentric Castleman Diseases in a HIV-Negative Patient

Arturo González Raya, Eva Martín Salido, Miguel Cantero Sánchez, Gonzalo Callejón Martín, María L. Hortas Nieto

Department of Clinical Laboratory, Agencia Sanitaria Costa del Sol, Marbella (Málaga), Spain

 

ABSTRACT

The Hemophagocytic syndrome (HS) is a very rare and aggressive disorder characterized by strong immunological activation of the mononuclear phagocyte system sometimes triggered by viral infections such as Epstein-Barr Virus. Castleman disease is a heterogeneous group of lymphoproliferative disorders associated in some cases with the human immunodeficiency virus (HIV) and human Herpes Virus 8 (HHV-8). The association of HHV-8, Multicentric Castleman Disease (MCD) and Hemophagocytic Syndrome is extremely rare. There are very few reported cases in literature, mostly in HIV positive elderly patients with fatal prognosis.We report a case of Hemophagocytic syndrome, HHV-8 and MCD on an HIV negative young adult. J Microbiol Infect Dis 2017; 7(4):202-206

Keywords: Hemophagocytic syndrome, Multicentric Castleman Disease, Herpes virus 8, HIV

Volume 07, Number 04 (2017)