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Abstract - Intestinal parasitic infections in leukemic patients with diarrhea
Serhat Uysal, Eylem Akdur, Varol Tunalı, Ayşe Uysal, Ayşegül Ünver, Güray Saydam, Meltem Taşbakan, Hüsnü Pullukçu, Nevin Turgay, Bilgin Arda

Intestinal parasitic infections in leukemic patients with diarrhea

Serhat Uysal1, Eylem Akdur Öztürk2, Varol Tunalı2, Ayşe Uysal3, Ayşegül Ünver2, Güray Saydam3, Meltem I Taşbakan1, Hüsnü Pullukçu1, Nevin Turgay2, Bilgin Arda1

1Infectious Diseases and Clinical Microbiology Department, Ege University, Faculty of Medicine, Izmir, Turkey

2Department of Clinical Parasitology, Ege University, Faculty of Medicine, Izmir, Turkey

3Hematology Department of Internal Medicine, Ege University, Izmir, Turkey

 

ABSTRACT

Objectives: Leukemic patients are at increased risk of severe infections with parasites. Moreover, intestinal parasites can lead to severe diarrhea in patients with immunosuppression. The purpose of this study is to decide intestinal parasitic infections and clinical aspects in leukemic patients.

Methods: Analysis was done of all leukemic patients hospitalized between January 2007 and October 2015 retrospectively.

Results: Ninety-one patients were evaluated. Intestinal parasites were diagnosed in nine (9.9%) patient. Cryptosporidium was the most frequently identified parasite, recovered from six specimens (6.6%), while Blastocystis (n=3) and Entamoeba (n=1) accounted for 3.3% and 1.1%, respectively. Cryptosporidium spp. and E. histolytica were detected together in one patient. Duration of diarrhea in patients with and without parasite were 16.1±9.3 and 7.9±2.9days, respectively (P=0.037). Abdominal cramps in patients with and without parasite were present in seven (77.8%) and 20 (24.4%) patients, respectively (P=0.002). In contrast, vomiting in patient with and without parasite were present in five (55.6%) and 81 (98.8%) patients, respectively (P<0.0005).

Conclusion: Parasitic infections should be considered for differential diagnosis in leukemic patients with diarrhea. J Microbiol Infect Dis 2017; 7(2): 63-66

Keywords: Intestinal Diseases, Leukemia, Parasitic, Diarrhea

Volume 07, Number 02 (2017)